Table 2.
Peptide Number | Amino Acid Sequence | Predicted HLA Class II preferences |
---|---|---|
1 a | LGYYFSDLNFQAPMVVTSS | DRB1*01, DRB1*04, DRB1*11, DRB1*15 |
2 | TVDVKNKRTFLSPWI | DRB1*04, DRB1*08, DRB1*11, DRB1*13 |
3 a | SSTVAIDHSLSLAGE | DRB1*03, DRB1*15 |
4 a | NANIRYVNTGTAPIYNV | DRB1*01, DRB1*03, DRB1*04, DRB1*07, DRB1*08, DRB1*11, DRB1*13 |
5 | LDKIKLNAKMNILIR | DRB1*03, DRB1*11, DRB1*13 |
6 a | KMNILIRDKRFHYDR | DRB1*08, DRB1*11, DRB1*13 |
7 | RYDMLNISSLRQDGK | DRB1*04, DRB1*11, DRB1*13 |
8 | DKDIRKILSGYIVEI | DRB1*04, DRB1*07, DRB1*15 |
9 a | KLPLYISNPNYKVNV | DRB1*01, DRB1*03, DRB1*07, DRB1*11, DRB1*13 |
10 | ISSLRQDGKTFIDFK | DRB1*03, DRB1*11 |
This sequence, predicted independently with the in silico programs, is identical to or has significant sequence homology with published class-II restricted PA peptides [13], detected using tetramer staining.