Figure 1. Photographs of a wound on Day 6 in a db/db mouse treated with PDGF-BB.

Area wound closure was calculated as original wound area on Day 0– open wound area on Day ‘X’ (area inside inner circumference indicated by a red line). Area wound contraction was calculated as original wound area on Day 0– area including open wound and new epithelium on Day ‘X’ (area inside outer circumference indicated by a blue line).