Table 2. Hypoxia-regulated genes strongly related to carcinogenesis.
| GENE | ID | Role in cancerbiology | WM793B(Foldchange) | PC-3(Fold change) | SK-OV-3(Fold change) |
| ADM | 202912_at | Angiogenesis | +4.9 | +20.1 | +17.5 |
| ANG | 205141_at | Angiogenesis | +5.5 | +2.7 | +11.4 |
| ANGPTL4 | 223333_s_at | Angiogenesis | +11.4 | +93.7 | +42.4 |
| ATF3 | 202672_s_at | Pro- and antitumorogenic,invasiveness | +2.06 (p = 0.0022) | +7.4 | –7.3 |
| BRAF | 206044_s_at | Main oncogene inmelanoma | +3.55 (p = 0.0055) | - | - |
| BRCA1 | 211851_x_at | DNA repair, stabilitygene | –4.1 | - | - |
| BRCA1 | 204531_s_at | DNA repair, stabilitygene | –3.9 (p = 0.0036) | –3.45 | - |
| BRCA2 | 214727_at | DNA repair, stabilitygene | –2.2 | - | - |
| CADM1 | 209032_s_at | Tumor suppressor | - | - | +4.5 |
| CXCL12 | 209687_at | Drug resistance,metastatic spreading | –10.9 | - | - |
| CXCR4 | 217028_at | Drug resistance,metastatic spreading | - | +25.6 | +264.1 |
| CXCR7 | 212977_at | Drug resistance,metastatic spreading | - | +10.5 | +38.15 |
| EREG | 205767_at | Proliferation, cellsurvival | - | - | –12.7 |
| FGF1 | 1552721_a_at | Proliferation,resistance to celldeath, angiogenesis,invasiveness | - | +16.6 | - |
| FN1 | 210495_x_at | Adhesion, migration,invasiveness | +2.0 (p = 0.0013) | +1.3 | - |
| ICAM2 | 213620_s_at | Immune surveillance | – | - | +10.4 |
| KITLG | 226534_at | Tumor growth, anti-apoptosis | – | - | +4.06 |
| LOX | 215446_s_at | Metastasis,nvasiveness, EpithelialMesenchymalTransition (EMT), | +4.7 | +4.4 | +1.7 |
| MCAM | 209087_x_at | Invasiveness, tumorsuppressor | - | –2.15 | - |
| MCAM | 211042_x_at | Invasiveness, tumorsuppressor | –2.1 | –2.3 | +1.9 |
| NEDD9 | 202149_at | Invasiveness, metastasis | - | –2.55 | +5.7 |
| NME1 | 201577_at | Metastasis suppressor | –1.6 (p = 0.0033) | –2.7 | - |
| OSMR | 1554008_at | Invasiveness, | +5.8 | - | +7.9 |
| SERPINE1 | 202628_s_at | Invasiveness, metastasis | - | +1.7 | +10.8 |
| SERPINE1 | 202627_s_at | Invasiveness,metastasis | - | +6.4 | +17.4 |
| STAT1 | 200887_s_at | Proliferation, cellgrowth | –1.7 | –2.45 (p = 0.0013) | +2.2 |
| WISP2 | 205792_at | Tumor suppressor inbreast and pancreaticcancer | - | - | +183.4 |
“+” and “–” signify increase and decrease in expression, respectively.