Table 2. Recovered flukes and assessment of macroscopic hepatic lesions in CD1 mice immunised with synthetic peptides containing B- and T-cell epitopes using the ADAD vaccination system and challenged with 7 F. hepatica metacercariae.

Group	Treatment	Number of flukes in individual mice	Worm recovery (Mean ± SEM)	Reduction (%)	Hepatic lesion in individual mice	Lesion score (Mean ± SEM)	Reduction (%)
1	Untreated uninfected
2	Infected	3, 1, 2, 2, 2	2.0±0.3		14, 14, 12, 10, 10	12.0±1.5
3	Adjuvant treated	0, 2, 0, 2, 2, 0	1.0±0.4	50	10, 14, 5, 11, 14, 2	9.3±1.8	22
4	B1	1, 0, 1, 2, 1, 1, 1	1.0±0.2	50	10, 12, 6, 11, 6, 9, 11	9.3±1.5	23
5	B2	0, 1, 1, 1, 1, 1	0.8±0.2	58	6, 14, 5, 9, 9, 5	8.0±1.3	33
6	B5	1, 0, 1, 0, 2, 0	0.7±0.3	67*	4, 1, 12, 12, 7, 8	7.3±2.1	39*
7	B6	2, 0, 2, 1, 0, 1	1.0±0.3	50	13, 2, 8, 10, 14, 13	10.0±1.7	17
8	T14	0, 1, 2, 1, 1, 0, 1	0.9±0.3	57	4, 7, 10, 13, 14, 9, 10	9.6±1.8	20
9	T15	0, 2, 0, 1, 2, 0	0.8±0.4	58	6, 14, 5, 4, 14, 10	8.8±1.7	26
10	T16	1, 0, 0, 1, 2, 1, 1	0.9±0.3	57	10, 10, 11, 5, 13, 12 14	10.7±1.1	11

*p<0.05 compared to infected controls.