Skip to main content
. 2014 Aug 14;10(8):e1004248. doi: 10.1371/journal.ppat.1004248

Figure 6. The gp41 TMD reduces serum cytokine levels in vivo and protects from consequential spleen damage.

Figure 6

(A–B) Blood serum TNFα and IL-6 levels of PBS, gp41 TMD and gp41 mutant treated mice estimated 90 minutes and 210 minutes after LTA minutes and 210 minutes after LTA minutes after LTA/GLN injection (n = 9, ** - p<0.005, ***-p<0.0005). (C) H&E staining of spleen sections of control (top), LTA and no peptide (middle) and LTA and gp41 TMD treated (bottom) mice. Apoptotic foci in the white pulp are indicated in circles and red pulp as squares. Scale bars = 200 µm and 400 µm for left and right panels, respectively.