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. Author manuscript; available in PMC: 2014 Aug 14.
Published in final edited form as: Aging Cell. 2010 Oct;9(5):799–809. doi: 10.1111/j.1474-9726.2010.00619.x

Figure 2. PG Inhibits Dox Induced Caspases.

Figure 2

Primary cultured cardiomyocytes were treated with 0.8 μM Dox for 24 hrs following pretreatment of PG at indicated dose for 24 hrs (A) or at 10 μM over indicated time (B). For Dox dose response, cardiomyocytes were treated with 10 μM PG and Dox at indicated doses for 16 hrs (C). Following pretreatment with 10 μM PG in the absence or presence of 10 μM 17β-estradiol (ES) or 10 μM testosterone (TS), cells were treated with 0.8 μM Dox for 24 hrs before harvesting for measurements of caspase activity (D, E). The data are from one experiment representative of three with means ± standard deviations from three samples. A superscript letter indicates significant difference (P<0.05) from means labeled with a different letter as determined by ANOVA analysis.