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. Author manuscript; available in PMC: 2014 Aug 14.
Published in final edited form as: Aging Cell. 2010 Oct;9(5):799–809. doi: 10.1111/j.1474-9726.2010.00619.x

Figure 4. PR Receptor Antagonist MF Blocks Cytoprotective Effect of PG.

Figure 4

Primary cultured cardiomyocytes were treated with 10 μM PG in the absence or presence of 1 μM MF for 24 hrs before addition of 0.8 μM Dox. The cells were harvested at 24 hrs later for measurements of caspase 3 using DEVD-AMC as a substrate (A), or for Western blot to measure caspase-3 cleavage or mitochondrial release of cytochrome c (B, C). A superscript letter indicates significant difference (P<0.05) from means labeled with a different letter as determined by ANOVA analysis.