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. Author manuscript; available in PMC: 2014 Aug 14.
Published in final edited form as: Aging Cell. 2010 Oct;9(5):799–809. doi: 10.1111/j.1474-9726.2010.00619.x

Figure 9. Cardioprotective Effect of PG Is Dependent on Bcl-xL.

Figure 9

Primary cultured cardiomyocytes were transfected with Bcl-xL siRNA or negative control siRNA as described in the Methods. At 48 hrs after siRNA transfection, cells were collected to verify Bcl-xL down regulation (upper panel) by Western blot with vinculin (bottom panel) as a loading control (A) or were pretreated with 10 μM PG for 24 hrs prior to 16 hrs treatment with 1 μM Dox for measurement of caspase-3 activity (B). The data is from one experiment representative of three. A superscript letter indicates significant difference (P<0.05) from means labeled with a different letter as determined by ANOVA analysis.