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. 2014 Sep 18;5(4):516–536. doi: 10.5312/wjo.v5.i4.516

Table 2.

The examined interleukin and interleukin receptor gene polymorphisms that are associated with rheumatoid arthritis

Gene Polymorphism Population Ref.
IL-1B rs16944 Algerian, British, Turkish [34,35,40]
rs1143623 British [35]
rs1143634 Algerian, Asian, Turkish [34,40-42]
IL1-RN rs419598 Black South Africans [36]
IL-2/IL-21 rs907715 Australasian [72]
rs6822844 Australasian, Dutch [65,72]
rs17388568 Australasian [72]
IL-2RA rs2104286 Dutch [64]
IL-4 rs2243250 Egyptian, Polish [51,52]
IL-4R rs1801275 African American, Egyptian [54,55]
rs1805010 African American, Egyptian [54,55]
IL-6 rs1800795 Iranian, United Kingdom, Spain, Spanish, Turkish [34,114,116, 117,122]
rs1800796 Han Chinese, Taiwan, Turkish [34,43,47,118]
IL-8 rs112664 Taiwan [118]
rs2227306 Caucasian [137]
IL-10 rs1800871 Malaysian, Polish [80,81]
rs1800872 Chinese, Malaysian, Polish [80-82]
rs1800896 Malaysian, Polish [80,81]
IL-15 rs2322182 North European [59]
rs4371699 North European [59]
rs6821171 North European [59]
rs7665842 North European [59]
rs7667746 North European [59]
IL-17A rs1974226 Japanese [136]
rs2275913 Norwegian [135]
rs3748067 Japanese [136]
rs3804513 Japanese [136]
IL-17F rs763780 Polish [134]
rs2397084 Polish [134]
IL-18 rs187238 Chinese, Egyptian [46,47]
rs549908 Taiwan [48]
rs360718 Japanese [49]
rs360722 Japanese [49]
rs1946518 Chinese, Egyptian, Japanese [46,47,49]
IL-23R rs1004819 European, New Zealand, Spanish [97,100,106]
rs1343151 European, New Zealand, Spanish [97,100,106]
rs1495965 Spanish [97]
rs2201841 European, New Zealand, Hungarian [96,97,100,106]
rs7517847 European, New Zealand, Spanish [97,100,106]
rs7530511 Caucasian [98]
rs10889677 Hungarian [96]
rs11209026 European, Caucasian, New Zealand [98,100,106]
rs11209032 Spanish [97]
rs10489629 Europan, New Zealand, Spanish [97,100,106]