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. 2014 Jul 1;124(7):1099–1109. doi: 10.1182/blood-2014-04-570770

Figure 4.

Figure 4

Inhibition of apoptosis increases the frequency of ASCs in preneoplastic v-abl mice. The total number of ASCs in the (A) spleen and (B) bone marrow (per femur) of healthy young mice (7-8 weeks) was determined by ELISPOT assay; total tissue cellularity is shown in supplemental Figure 2. bim−/−v-abl and littermates (white fill), n = 3 to 6; mcl-1/v-abl and littermates (gray fill), n = 10 to 12; bcl-2/v-abl and littermates (black fill), n = 8. Mean ± SEM. *P < .05, **P < .01, ***P < .001, Student t test. Statistical analysis for WT vs bim−/−v-abl and v-abl vs bim−/− are not shown.