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Echinomycin treatment does not affect long-term HSC activity as revealed by composition of spleen cells. Spleen cells from the CD45.2+ recipients of competitive BMT were analyzed for composition of CD45.1+ donor-type leukocytes. (A) Frequency of CD45.1+ cells. (B) Frequency of B and T cells. (C) Frequency of granulocytes. (D) Summary data of A-C. Data shown represent the mean and standard error of the mean for 5 mice. These data have been repeated in 2 independent experiments.
