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. 2014 Aug 15;5(3):228–238. doi: 10.4291/wjgp.v5.i3.228

Table 3.

Distribution of similarities and differences in the differential diagnosis of Behçet’s disease and Crohn’s disease[2,3,6,8,9,14,58,60,62,68,81]

Behçet’s Disease Crohn’s Disease
Gender (M/F) 4.9-0.57 2.9-0.76
Symptoms onset age (yr) 20.8-40 15-29
Average age at diagnosis (yr) 24.7-35.7 29.5-31
Oral aphtous ulcers (%) Approximately 100 < 10
Uveitis (%) 57-69 < 10
Skin lesions (%) 61-87 < 10
Arthritis (%) 30-57 2-24.7
Gastrointestinal involvement (%)
Ileocecal area 50-94 40-83
Colon 10-15 32-50
Upper GI 1-3 4
Perianal 1-2 10-15
Intestinal complications (%)
Perforation 12.7 8.7
Fistula 7.6 24.7
Stricture 7.2 38.3
Abscess 3.3 19.6
Endoscopic Morphology Round-oval shape, Longitudinal ulcers with a cobblestone appearance
Focal, solitary (segmental and diffuse distribution)
Volcano-shaped
Deep ulcers
Mucosal Biopsy Vasculitis Granuloma
Neutrophilic infiltration Focal cryptitis
Fibrinopurulent exudates Nerve fiberhyperplasia
Necrotic debris Lymphoid aggregates