Table 1.
Staining scores for stem cell markers in human gastric mucosa and rat gastric mucosa
| n | ALDH | CD166 | LGR5 | |
| Normal | 10 | 1-2 | 0 | 1-2 |
| H. pylori without IM | 12 | 5-6a | 3-4a | 3-4a |
| H. pylori with IM | 10 | 7-8a | 5-6a | 5-6a |
| Gastric adenocarcinoma | 12 | 85% | 75% | 70% |
| 4-mo-old rat | 6 | 1-2 | 1-2 | 0 |
| 24-mo-old rat | 6 | 3-4 | 5-6a | 3-4a |
The numbers are cells expressing the marker per a crypt counted. We grouped the cell counts as 0; 1-2; 3-4; 5-6; 7-8; etc. For evaluation of gastric adenocarcinoma, we expressed the percentage of cells staining with the related marker.
a
P < 0.05 vs normal human gastric mucosa or 4-mo-old rat gastric mucosa. Gastric adenocarcinoma was not included in statistical analysis.