TABLE 3. Serum Hormone Levels (Mean ± SE)*.

	Estradiol (pg/ml)	Testosterone (ng/dl)	T3 (ng/dl)	T4 (μg/dl)a	Corticosterone (ng/ml)a	Ghrelin (ng/ml)	Leptin (ng/ml)
Males
Naïve control (n = 12)	13.60 ± 2.67	359.020 ± 43.965	57.65 ± 3.72	4.198 ± 0.318	217.70 ± 17.00	1.01 ± 0.13	7.18 ± 1.50
Vehicle control (n = 12)	14.47 ± 3.15	339.730 ± 45.491	57.79 ± 4.22	4.180 ± 0.196	219.3 ± 19.0	0.99 ± 0.13	6.75 ± 1.32
2.5 BPA (n = 11)	15.21 ± 2.05	339.313 ± 63.267	47.81 ± 4.92	3.724 ± 0.311	193.1 ± 23.6	0.90 ± 0.11	5.62 ± 0.79
25.0 BPA (n = 12)	16.15 ± 2.50	442.343 ± 71.402	56.78 ± 4.43	4.578 ± 0.158	176.5 ± 22.4	1.13 ± 0.21	4.05 ± 0.57
5.0 EE2 (n = 11)	15.23 ± 2.95	118.387 ± 26.074†	46.61 ± 5.02	4.277 ± 0.362	160.5 ± 19.5	1.11 ± 0.21	5.61 ± 0.84
10.0 EE2 (n = 12)	16.29 ± 3.20	108.779 ± 19.916†	59.66 ± 4.67	4.764 ± 0.330	207.3 ± 18.5	0.99 ± 0.18	8.37 ± 1.75
Females
Naïve control (n = 12)	15.88 ± 3.17	4.346 ± 0.29	55.37 ± 3.44	2.914 ± 0.191	385.9 ± 20.5	1.13 ± 0.24	4.09 ± 0.94
Vehicle control (n = 12)	11.96 ± 1.65	4.00 ± 0.00	49.27 ± 4.84	2.914 ± 0.170	334.7 ± 35.7	1.28 ± 0.30	4.20 ± 1.40
2.5 BPA (n = 11)	23.52 ± 4.57	4.97 ± 0.660	52.98 ± 5.45	3.029 ± 0.308	383.8 ± 19.7	1.22 ± 0.28	3.88 ± 0.83
25.0 BPA (n = 12)	15.34 ± 2.45	4.41 ± 0.34	63.32 ± 5.46	3.473 ± 0.231	358.2 ± 34.2	0.86 ± 0.17	6.43 ± 1.62
5.0 EE2 (n = 10)	16.39 ± 2.43	4.35 ± 0.35	64.48 ± 8.45	3.2707 ± 0.2933	339.7 ± 26.6	1.02 ± 0.20	7.59 ± 1.92
10.0 EE2 (n = 12)	18.96 ± 3.24	4.00 ± 0.00	58.24 ± 4.78	3.7478 ± 0.2486	313.7 ± 29.6	1.08 ± 0.25	5.75 ± 1.60

^aSignificant sex effects indicated higher T4 levels in males and higher corticosterone levels in females (neither interacted significantly with treatment).

*Data for LH are not shown as only one subject's level (a vehicle control female) was above the detection limit of 0.15 mIU/ml.

^†Significantly lower than vehicle control males.