Figure 6.
Enhanced basal ICa but blunted beta-adrenergic response in ≥4-month-old mdx myocytes. ICa–voltage curves in 2- (A), 3- (B), 4- (C), and 12-month (D) control and mdx VMs before and after ISO. *P < 0.05, before vs. after ISO in control myocytes at the same test voltage at baseline; #P < 0.05, before vs. after ISO in mdx myocytes at the same test voltage; &P < 0.05, mdx vs. control at the same test voltage at baseline. Two-way ANOVAs with repeated measurements and post hoc test (Bonferroni corrections) were performed within the same age group.