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. 2014 May 8;103(1):60–71. doi: 10.1093/cvr/cvu119

Figure 8.

Figure 8

PKA activity with or without ISO stimulation and beta-adrenergic receptors (β1-AR and β2-AR) abundance in 4-month-old mdx and control hearts. (A) PKA activity in 4-month-old control and mdx hearts without or with ISO. Western blots (B) and abundance (C) of β1-AR and β2-AR in 4-month-old control and mdx hearts. (D) Contractions of 4-month-old control and mdx myocytes in response to different doses of ISO. Student's t-test was used for (C); two-way ANOVAs with the post hoc test were performed for (A) and also with repeated measurements for (D). *P < 0.05, **P < 0.01 control vs. mdx at the same ISO dose; $P < 0.05, $$$P < 0.001 at the indicated dose of ISO vs. baseline in control myocytes; #P < 0.05, ###P < 0.001 at the indicated dose of ISO vs. baseline in mdx myocytes.