Table 5.
Example of sample size calculation for the joint test under PH
| Power of test under PH | Target HR | Sample size | ||
|---|---|---|---|---|
| Logrank | Joint | n | events | |
| 0.8 | 0.709 | 0.70 | 378 | 248 |
| 0.75 | 570 | 380 | ||
| 0.80 | 931 | 632 | ||
| 0.9 | 0.835 | 0.70 | 506 | 332 |
| 0.75 | 763 | 509 | ||
| 0.80 | 1246 | 845 | ||
| 0.874 | 0.8 | 0.70 | 464 | 304 |
| 0.75 | 700 | 467 | ||
| 0.80 | 1142 | 775 | ||
| 0.945 | 0.9 | 0.70 | 610 | 399 |
| 0.75 | 919 | 613 | ||
| 0.80 | 1500 | 1018 | ||
The power for the logrank test is given in the first column. The corresponding power of the joint test is shown in the second column.