Table 4.
Predictive factors of complicated diseases in patients with EV71 infection
| Uncomplicated EV71 infection (Grade 1) (n = 88) | Complicated EV71 infection (Grade 2 to 4) (n = 136) | pvaluea | |
|---|---|---|---|
| Age (median with range, years) | 3.08 (0–15) | 2.60 (0–14) | 0.06 |
| Gender | |||
| Male | 56 (64%) | 84 (62%) | 0.89 |
| Female | 32 (36%) | 52 (38%) | |
| Fever b | 72 (82%) | 132 (97%) | <0.001 |
| Fever > 3 days | 34 (39%) | 83 (61%) | 0.002 |
| Skin rash | 86 (97%) | 124 (94%) | 0.21 |
| Oral ulcer | 85 (97%) | 132 (97%) | 1.00 |
| Viremia | |||
| Yes | 23 (26%) | 36 (26%) | 0.96 |
| No | 65 (74%) | 100 (74%) | |
| Viral load (median with range, log10 copies/mL) | 3.34 (0.88 - 6.99) | 3.50 (1.29 - 6.51) | 0.80 |
Values expressed as n(%), unless otherwise indicated.
aThe chi-square and Fisher’s exact test was used for categorical variables, and the Mann–Whitney test was used for comparison of the viral load.
bFever was defined as any body temperature over 38 degrees Celsius.