Table 5.

Multivariate analysis of risk factors of complicated EV71 disease (grade 2 to 4)

	Odds ratio	95% CIs	pvalue
Age <1 year	2.57	0.87 - 7.62	0.09
Sex (Male)	0.99	0.86 - 1.15s	0.92
Skin rash	0.29	0.05 - 1.54	0.15
Fever a	5.63	1.74 - 18.28	0.001
Oral ulcer	1.91	0.31 - 11.74	0.48
Day of illness on sampling (day)	1.05b	0.84 - 1.31	0.66
Viremia	1.26	0.61 - 2.59	0.54

^aFever was defined as any body temperature over 38 degrees Celsius.

^bThe value represents the change in odds ratio per day after disease onset.