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. 2014 Feb 17;40(5):1154–1163. doi: 10.1093/schbul/sbt154

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© The Author 2014. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/3.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 2. — Meta-analyses of association studies between the blood homocysteine levels and schizophrenia. (A) The result of the meta-analysis of 12 male association studies (N = 2638). The blood homocysteine levels were significantly higher in male patients with schizophrenia than in the male controls (standardized mean difference [SMD] = 0.76; 95% CI = 0.30–1.22; P = 1.2×10^–3 in the random-effects model). (B) The result of the meta-analysis of 10 female association studies (N = 2076). The blood homocysteine levels were significantly higher in female patients with schizophrenia than in the female controls (SMD = 0.50; 95% CI = 0.31–0.70; P = 5.9×10^–7 in the random-effects model).