Table 2. Sociodemographic and clinicopathological parameters of EIF3E amplifications with OSCC cases.
EIF3E | ||||
---|---|---|---|---|
Parameters | N | Amplified (%) | Not Amplified (%) | P value (Fisher's exact test) |
Sex | ||||
Male | 13 | 6 (46.2) | 7 (53.8) | 0.107 |
Female | 20 | 3 (15.0) | 17 (85.0) | |
Ethnicity | ||||
Indian | 16 | 2 (12.5) | 14 (87.5) | 0.118 |
Others | 17 | 7 (41.2) | 10 (58.8) | |
Alcohol Drinking | ||||
Drinkers | 10 | 4 (40.0) | 6 (60.0) | 0.40 |
Non-drinkers | 23 | 5 (21.7) | 18 (78.3) | |
Smoking | ||||
Smokers | 7 | 4 (57.1) | 3 (42.9) | 0.068 |
Non-smokers | 26 | 5 (19.2) | 21 (80.8) | |
Betel Quid Chewing | ||||
Chewers | 18 | 2 (11.1) | 16 (88.9) | 0.047 |
Non-chewers | 15 | 7 (46.7) | 8 (53.3) | |
Habits | ||||
Yes | 26 | 6 (23.1) | 20 (76.9) | 0.358 |
No | 7 | 3 (42.9) | 4 (57.1) | |
Tumour Sub-sites | ||||
Tongue | 18 | 6 (33.3) | 12 (66.7) | 0.458 |
Others (Buccal) | 15 | 3 (20.0) | 12 (80.0) | |
Tumour Size | ||||
T1 & T2 | 18 | 5 (27.8) | 13 (72.2) | 1.00 |
T3 & T4 | 12 | 4 (33.3) | 8 (66.7) | |
Lymph Node Status | ||||
Positive | 11 | 0 (0.0) | 11 (100.0) | 0.012 |
Negative | 20 | 9 (45.0) | 11 (55.0) | |
TNM Staging | ||||
Stage I/II | 12 | 5 (41.7) | 7 (58.3) | 0.240 |
Stage III/IV | 20 | 4 (20.0) | 16 (80.0) | |
Histological Grading | ||||
Well differentiated | 14 | 4 (28.6) | 10 (71.4) | 1.00 |
Moderate differentiated | 17 | 5 (29.4) | 12 (70.6) |