Skip to main content
. 2014 Jul 25;3(8):777–784. doi: 10.1242/bio.20149399

Fig. 5. Glycolate and D-lactate support viability of dopaminergic neurons in vitro.

Fig. 5.

(A) Viability of the dopaminergic neurons in vitro from wild-type and DJ-1 mutant mice embryos in the presence or absence of 10 mM glycolate (GA), D-lactate (DL), or L-lactate (LL). Points show the ratio of tyrosine hydroxylase-positive (TH+) cells to the control (no supplement). Horizontal blue bars and error bars represent the mean and SD, respectively. **p<0.01; ***p<0.001. (B) Viability of the dopaminergic neurons in the presence of 12.5 µM paraquat (PQ2+) in the absence or presence of 10 mM GA, DL, or LL. Primary neurons isolated from wild-type E14.5 embryos were cultured in vitro in the presence of the indicated supplements and PQ2+. Points show the ratio of TH+ cells to the control. Horizontal blue bars and error bars represent the mean and SD, respectively.