Fig. 1. Schematic of algorithm utilizing smear-microscopy alone versus algorithm utilizing Xpert with LF-LAM.
Schematic diagram of decision analysis model for TB diagnostic algorithms with and without Xpert and/or LF-LAM. Not all branches are shown. Schematic for algorithm 2 (Smear/LF-LAM) and algorithm 3 (Xpert alone) are shown in Supplemental content 1. *Individuals are eligible to return to clinic/hospital for repeat evaluation, with incremental increases in diagnosis. We assumed increased TB treatment mortality for individuals with delayed diagnoses (Supplemental Content for additional model and parameters). DALYs, disability-adjusted life years; DST, drug sensitivity testing.