Table 1.
Percent of mothers with titers >0.35 mcg/mL |
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12 month/delivery geometric mean ratios |
Delivery |
12 months post-delivery |
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Serotype | 23vPPS vaccinees | Controls | P value | 23vPPS | Control | P value | 23vPPS | Control | P value |
4 | 0.67 | 1.76 | 0.0003 | 86.4 | 30.0 | <0.0001 | 88.3 | 55.0 | <0.0001 |
6B | 0.80 | 2.16 | <0.0001 | 91.5 | 61.7 | 0.0001 | 95.0 | 90.0 | 0.2985 |
9V | 0.77 | 1.80 | <0.0001 | 96.6 | 71.7 | 0.0002 | 96.7 | 93.3 | 0.4022 |
14 | 0.72 | 1.74 | <0.0001 | 93.2 | 66.7 | 0.0003 | 90.0 | 85.0 | 0.4076 |
19F | 0.58 | 1.44 | 0.0001 | 91.7 | 40.0 | <0.0001 | 85.0 | 53.3 | 0.0002 |
18C | 0.93 | 2.18 | <0.0001 | 88.3 | 51.7 | <0.0001 | 86.7 | 73.3 | 0.0679 |
23F | 0.82 | 2.28 | <0.0001 | 90.0 | 65.0 | 0.001 | 95.0 | 78.3 | 0.0072 |
1 | 1.32 | 2.25 | 0.0162 | 100.0 | 96.7 | 0.1538 | 100.0 | 100.0 | N/A |
5 | 1.10 | 2.47 | <0.0001 | 100.0 | 85.0 | 0.0018 | 98.3 | 95.0 | 0.3091 |
Mean GMR | 0.83 | 1.98 | <0.0001 |
Abbreviations: 23vPPS, 23-valent pneumococcal polysaccharide; GMR, geometric mean ratio.