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. Author manuscript; available in PMC: 2014 Aug 15.
Published in final edited form as: Nature. 2013 Oct 30;503(7475):277–280. doi: 10.1038/nature12746

Extended Data Figure 2.

Extended Data Figure 2

SGA analysis of selected SHIVAD8EO gp120 sequences, present in rebound virus following single mAb immunotherapy, and known to confer resistance to 10-1074 or 3BNC117 mAb. SGA was used to amplify plasma viral RNA following mAb treatment from the plasma of animals KZ6 [day 28], MB6 [day 23], MB8 [day 23], and MCN [day 23]. The gp120 sequences at the top are present in the SHIVAD8EO molecular clone inoculum. Mutations conferring resistance are highlighted in red.