Table 1.
SHIVAD8 infected macaques treated with anti-HIV mAbs
Animal | Pre-Infection | Treatment Initiation | Pre mAb Treatment | Clinical Status | mAb Administered | ||
---|---|---|---|---|---|---|---|
CD4+ T Cells (Cells/µl) |
Weeks Post Infection | CD4+ T Cells (Cells/µl) |
Viral Load (RNA Copies/ml) |
3BNC117 (mg/kg) |
10-1074 (mg/kg) |
||
KZ6 | 881 | 12 | 1447 | 5.22E+03 | Post-Acute Set Point | 10 | 0 |
MB6 | 545 | 12 | 1598 | 7.43E+03 | Post-Acute Set Point | 10 | 0 |
MB8 | 1512 | 12 | 2625 | 1.14E+04 | Post-Acute Set Point | 0 | 10 |
MCN | 210 | 12 | 599 | 2.14E+04 | Post-Acute Set Point | 0 | 10 |
DBZ3 | 650 | 159 | 118 | 1.08E-04 | Asymptomatic | 10 | 10 |
DC99A | 623 | 159 | 165 | 7.60E+03 | Asymptomatic | 10 | 10 |
DBXE | 1585 | 163 | 158 | 1.96E+05 | Intermittent diarrhea | 10 | 10 |
DCF1 | 1203 | 157 | 105 | 1.44E+05 | Intermittent diarrhea | 10 | 10 |
DCM8 | 608 | 163 | 43 | 1.59E+0. | Intermittent diarrhea | 10 | 10 |