Table 1.
Clinical data of patients with neuroendocrine tumors
| Patient (age, yr/sex) | Initial evaluation | Site | Diagnostic studies | Outcome |
| 65/F | Hematochezia, IBD epigastric pain | Duodenal bulb | 12 21 05 EGD duodenal bulb polyp; path: neuroendocrine tumor 12 30 05 repeat EGD, no residual, path: neuroendocrine tumor 11 24 08 repeat EGD no recurrence, COL mucosal prolapse syndrome | Alive and well |
| 59/M | GERD with break-through symptoms | Duodenal bulb | 11 11 08 EGD duodenal bulb polyp, path: neuroendocrine tumor 12 22 08 EGD, no residual tumor 12 30 08 PET scan negative | Alive and well |
| 50/F | 2nd opinion for liver metastatic disease | Liver | 02 09 04 EGD chronic esophagitis, HH, fundic nodularity, path: benign lymphoid aggregates 03 16 04 PET/CT innumberable larg hepatic lesions replacing R and L lobes consistent with neuroendocrine tumor | Expired 12 04 |
| 70/M | Epigastric pain and 15 lb weight loss | Intra-abdominal | 04 15 08 EGD chronic esophagitis, HH, acute and chronic gastritis; path: reactive gastropathy; COL: 1 adenomatous/2 hyperplastic polyps 04 16 08 CT Abd/Pelvis mesen-teric mass 04 24 08 CT guided bx: path: neuroendocrine tumor | 05 08 treated with sandostatin |
| 46/F | Nausea, vomiting, abdominal pain | Intra-abdominal | 01 02 10 CT Abd/Pelvis ascites small bowel and colonic obstruction 01 04 10 Gastrografin emema sigmoid Obstruction 01 04 10 exploratory laparotomy desmoplastic reaction, sigmoid colon with liver metastases and intraperitoneal implants; bx of implants positive for chromogranin and synapotophysin 01 19 10 COL 3 cm stenosis at 30 cm due to extrinsic pressure; stent placed 01 26 10 serum CGA, 27 nmole/L | Discharge To hospice |
| 40/M | Recurrent perianal abscess r/o IBD | Terminal ileum | 12 05 06 COL 10 mm sessile polyp in terminal ileum, path: neuroendocrine tumor | Lost to follow-up |
| 50/F | GERD and CRCS | Sigmoid | 04 04 08 EGD chronic esophagitis, HH, path: mild reactive gastropathy, COL 4 mm sigmoid neuroendocrine tumor resected 04 30 08 normal octreotide scan 03 30 09 COL negative bx at prior polypectomy site | Alive and well |
| 75/F | Breast cancer and CRCS | Sigmoid | 02 06 08 COL 7 mm sigmoid submucosal nodule resected; cells positive for synaptophysin, but negative for chromogranin 03 11 08 Urinary 5-HIAA negative 04 22 08 Repeat COL with resection of remaining neuroendocrine tumor 05 19 09 COL negative for recurrence | Alive and well |
| 55/M | LLQ tenderness, CRCS | Rectum | 08 22 06 COL sigmoid tubulovillous adenoma and 6 mm rectal neuro-endocrine tumor 09 01 09 COL hyperplastic polyp, no recurrence of neuroendocrine tumor | Alive and well |
| 55/F | CRCS | Rectum | 05 01 09 COL 8 mm neuroendocrine tumor COL 1 yr later no recurrence | Alive and well |
| 60/F | CRCS | Rectum | 11 29 07 COL submucosal nodule neuroendocrine tumor 01 28 08 COL no recurrence | Alive and well |
IBD: Inflammatory bowel disease; CGA: Chromogranin A; EGD: Esophagoduodenoscopy; COL: Colonoscopy; GERD: Gastroesophageal reflux disease; HH: Hiatal hernia; R: Right; L: Left; bx: Biopsy; CRCS: Colorectal cancer screening; F: Female; M: Male; 5-HIAA: 5-hydroxyindoleacetic acid; PET/CT: Positron emission tomography/computed tomography; LLQ: Left lower quadrant.