Table 1.
Gene segment distribution in the genomes of reassortants generated from various influenza A and B viruses circulating in different years.
Influenza A Viruses | ||||||||
---|---|---|---|---|---|---|---|---|
Gene Segments | Before 20001 | After 20002 | ||||||
% | (n) | % | (n) | % | (n) | % | (n) | |
WT | MDV | WT | MDV | |||||
PB2 | 2,1% | (2) | 97,9% | (95) | 9,6% | (5) | 90,4% | (47) |
PB1 | 5,2% | (5) | 94,8% | (92) | 40,4% | (21) | 59,6% | (31) |
PA | 2,1% | (2) | 97,9% | (95) | 9,6% | (5) | 90,4% | (47) |
HA | 100,0% | (97) | 0,0% | (0) | 100,0% | (52) | 0,0% | (0) |
NP | 29,9% | (29) | 70,1% | (68) | 44,2% | (23) | 55,8% | (29) |
NA | 91,8% | (89) | 8,2% | (8) | 13,5% | (7) | 86,5% | (45) |
M | 42,3% | (41) | 57,7% | (56) | 65,4% | (34) | 34,6% | (18) |
NS | 47,4% | (46) | 52,6% | (51) | 80,8% | (42) | 19,2% | (10) |
Influenza B Viruses | ||||||||
Gene Segments | Before 20003 | After 20004 | ||||||
% | (n) | % | (n) | % | (n) | % | (n) | |
WT | MDV | WT | MDV | |||||
PB2 | 8,3% | (1) | 91,7% | (11) | 19,9% | (48) | 80,1% | (193) |
PB1 | 17,0% | (2) | 83,0% | (10) | 39,8% | (96) | 60,2% | (145) |
PA | 16,7% | (2) | 83,3% | (10) | 10,0% | (24) | 90,0% | (217) |
HA | 100,0% | (12) | 0,0% | (0) | 100,0% | (241) | 0,0% | (0) |
NP | 41,7% | (5) | 58,3% | (7) | 39,8% | (96) | 60,2% | (145) |
NA | 91,7% | (11) | 8,3% | (1) | 11,2% | (27) | 88,8% | (214) |
M | 50,0% | (6) | 50,0% | (6) | 90,0% | (217) | 10,0% | (24) |
NS | 66,7% | (8) | 33,3% | (4) | 78,0% | (188) | 22,0% | (53) |
Influenza A viruses:
1Reassortants of A/Leningrad/134/17/57 (H2N2) master donor virus (MDV) with A/Nanchang/933/95 (H3N2), A/Beijing/262/95 (H1N1), A/Perth/13/95 (H1N1), A/Johannesburg/82/96 (H1N1), A/Panama/2007/99 (H3N2), A/New Caledonia/20/99 (H1N1)
2Reassortants of A/Leningrad/134/17/57 (H2N2) MDV with A/Wellington/01/04 (H3N2), A/Malaysia/01/04 (H3N2), and A/Brisbane/10/07 (H3N2).
Influenza B viruses:
3Reassortants of B/USSR/60/69 MDV with B/Harbin/07/94, B/Shandong/7/97
4Reassortants of B/USSR/60/69 MDV with B/Florida/4/06, B/Brisbane/3/07, B/Bangladesh/1994/10, and B/Wisconsin/1/10