Table 4.
Statistical analyses of collected data using Pearson chi-square (χ2) test and Student’s t distribution test.
| Virus Tested | Sensitivity to Inhibitors1 | Comparison Groups | Number of Reassortants/Total | Pearson c2 Criterion | p Value |
|---|---|---|---|---|---|
| Efficiency of NA Inheritance by Reassortant Viruses | |||||
| All A viruses | Resistant | WT-NA | 220/268 | 80.74 | p < 0.0001 |
| Sensitive | 67/167 | ||||
| Resistant | MDV-NA | 48/268 | |||
| Sensitive | 100/167 | ||||
| All B viruses | Resistant | WT-NA | 77/88 | 143.90 | p < 0.0001 |
| Sensitive | 63/326 | ||||
| Resistant | MDV-NA | 11/88 | |||
| Sensitive | 263/326 | ||||
| All A and B viruses | Resistant | WT-NA | 297/356 | 269.21 | p < 0.0001 |
| Sensitive | 130/493 | ||||
| Resistant | MDV-NA | 59/356 | |||
| Sensitive | 363/493 | ||||
| Efficiency of Reassorting Into Vaccine-appropriate (6:2 and 5:3) Genomic Compositions | |||||
| All A viruses | Resistant | Vaccine genomic composition | 145/268 | 57.86 | p < 0.0001 |
| Sensitive | 29/167 | ||||
| Resistant | Other combinations | 123/268 | |||
| Sensitive | 138/167 | ||||
| All B viruses | Resistant | Vaccine genomic composition | 51/88 | 119.57 | p < 0.0001 |
| Sensitive | 24/326 | ||||
| Resistant | Other combinations | 37/88 | |||
| Sensitive | 302/326 | ||||
| All A and B viruses | Resistant | Vaccine genomic composition | 196/356 | 195.78 | p < 0.0001 |
| Sensitive | 53/493 | ||||
| Resistant | Other combinations | 160/356 | |||
| Sensitive | 440/493 | ||||