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IGF-I production by chondrocytes transfected or cotransfected using pAAV-based vectors. Articular chondrocytes were transfected by the designated plasmids (sets 3–7), or cotransfected simultaneously by the designated plasmid pair (set 8). Transfection by pAAV-MCS (empty vector) at matching concentrations was used as a control for transfection (set 1) and cotransfection (set 2) groups.
