Fig. 4.
Surface expression of Cr1, Cr2, CD19, CD40 and CD23 (FcεR2a) on B cells is modulated in Cr2KO mice. (a) Representative histograms of Cr1 (antibody clone: 8C12), Cr1/2 (7G6), Cr1/2 (8D9), CD19, CD23, and CD40 expression on B220+ cells from the spleens of WT (gray line), Cr2KO (black line), and Cr1/2KO mice (gray fill). (b) The average geometric mean fluorescent intensity (gMFI) is graphed for B220+ cells from WT, Cr2KO, and Cr1/2KO mice represented in (a). Significance determined by the t-test shown between bars by black lines and denoted by asterisks (*p < 0.05, **p < 0.01, ***p < 0.001, and ns = not significant). Data representative of 2–3 independent analyses and n = 5–9 for all graphs.
