Table 1.
Non-coding RNAs (ncRNAs) found in eukaryotic cells.
Name | Description | Length | Function | Ref. |
---|---|---|---|---|
rRNA | ribosomal RNA | 121-5070 nt | organize structure of ribosomal subunits 60S and 30S; crucial for translation | [6] |
tRNA | transfer RNA | 80 nt | transfer amino acids to a growing polypeptide chain during translation | [6] |
esiRNA | endogenous small interfering RNA | 21-22 nt | cleave mRNA | [7] |
miRNA | microRNA | 19-24 nt | prevent protein synthesis through RNA interference; catalyze gene modifications, including methylation, that modify gene transcription activity | [7, 8] |
piRNA | Piwi-interacting RNA | 26-31 nt | form RNA-protein complexes through interactions with Piwi (P-element induced wimpy testis) proteins; silence transposons | [8, 9] |
snoRNA | small nucleolar RNA | 60-300 nt | modify RNAs, including methylation and pseudo-uridylation of rRNA and tRNA; can act in regulation of gene expression | [10] |
lincRNA | long intergenic ncRNAs | > 200 nt | associate with chromatin-modifying complexes | [11] |
other lncRNA |
long ncRNAs | > 200 nt | regulate protein expression at the level of transcriptional or post-transcriptional processing and chromatin modification; involved in gene silencing; can act as enhancer RNAs | [4, 12] |