Table 3.
The serum levels of several oxidative stress markers before and after the initiation of the treatment with oral febuxostat.
| AFTER THE INITIATION OF ORAL FEBUXOSTAT TREATMENT | P VALUE | ||||
|---|---|---|---|---|---|
| BASELINE | 1 MONTH | 3 MONTHS | 6 MONTHS | ||
| Protein carbonyls (nmol/mg protein) | 0.07 (IR: 0.03–0.12) | 0.10 (IR: 0.06–0.14) | 0.07 (IR: 0.06–0.15) | 0.05 (IR: 0.03–0.11) | 0.329 |
| 3-NT (nM) | 30.4 (IR: 25.2–40.4) | 33.2 (IR: 25.5–42.2) | 37.3 (IR: 25.3–45.3) | 28.7 (IR: 24.7–43.9) | 0.928 |
| 8-OHdG (ng/ml) | 1.64 (IR: 1.24–2.95) | 2.51 (IR: 1.24–4.74) | 1.05 (IR: 0.84–1.87) | 0.54 (IR: 0.204–1.16)* | 0.002 |
Note:
*
P < 0.05 versus baseline.