Table 4.
Meta-analysis PheWAS results of rs8050136 for previously reported phenotypes associated with genetic variants.
| Phenotype | Cases | Not adjusted for BMI | Adjusted for BMI | ||
|---|---|---|---|---|---|
| p† | OR (95% CI) | p† | OR (95% CI) | ||
| Attention deficit hyperactivity disorder | 76 | 0.085 | 0.74 (0.52–1.04) | 0.11 | 0.75 (0.53–1.06) |
| Pancreatic cancer | 183 | 0.23 | 1.14 (0.92–1.40) | 0.19 | 1.15 (0.93–1.42) |
| Alcoholism | 267 | 0.37 | 1.08 (0.91–1.29) | 0.32 | 1.09 (0.92–1.30) |
| Senile dementia | 192 | 0.90 | 0.99 (0.80–1.22) | 0.90 | 0.99 (0.80–1.22) |
| Osteoarthritis | 6328 | 0.20 | 1.03 (0.98–1.08) | 0.88 | 1.00 (0.95–1.06) |
This table includes select phenotypes that have been previously reported in the literature. The Bonferroni alpha = 0.05 equates to a p-value of 4.95 × 10−5, and an FDR of q = 0.05 gives a p-value of 2.48 × 10−4. OR, Odds ratio; CI, confidence interval.
†
Values are not corrected for multiple testing.