Table 4.

Characteristics of persons for whom therapy is contraindicated.

Major uncontrolled depression

Solid organ transplant (renal, heart, lung)

Autoimmune hepatitis or other autoimmune condition, which can be exacerbated by peginterferon and ribavirin

Untreated thyroid disease

Pregnant or not willing to comply with adequate contraception

Severe medical diseases such as severe hypertension, heart failure, coronary artery disease, poorly controlled diabetes, chronic obstructive pulmonary disease

Age less than 2 years old

Hypersensitivity to drugs used to treat HCV