Table 3.
Haplotype | Freq | Unadjusted | Adjusted[1] | ||||
---|---|---|---|---|---|---|---|
|
|
||||||
HR | 95% CI | p-value | HR | 95% CI | p-value | ||
GCG | 0.46 | REF | REF | ||||
ATA | 0.39 | 1.54 | 1.14-2.09 | 0.006 | 1.46 | 1.05-2.03 | 0.023 |
ACG | 0.11 | 1.22 | 0.80-1.86 | 0.353 | 1.18 | 0.77-1.82 | 0.446 |
GTA | 0.04 | 2.42 | 1.21-4.83 | 0.012 | 2.19 | 1.06-4.52 | 0.035 |
Abbreviations: Freq estimated haplotype frequency, HR hazard ratio (per allele), CI confidence interval
Adjusted for year of diagnosis (1990-1999 / 2000-2008), sex (men / women), age at diagnosis (<55 / 55-64 / 65-69 / 70-74 / 75+), pack years (<35 / 35-49 / 50-74 / 75+), and stage (III / IV)