(A) Proliferation of
MC3T3-E1 cells after 4, 7, 10 and 12 days of incubation on different
PCL/HAp films, (b) topographically ordered, (c) topographically disordered
and (d) flat, normalized to proliferation on control cell culture
polystyrene (a). The proliferation ratio is represented as a number
of cells counted per surface area for a given sample (N) normalized to the number of cells per surface area for the control
sample (Nc). (B) MTT viability assay for
MC3T3-E1 cells on control cell culture polystyrene (a) and on different
PCL/HAp films, (b) topographically ordered, (c) topographically disordered
and (d) flat, after 1, 3, 7 and 12 days of incubation. Samples for
which a statistically significant difference (p <
0.05) was observed when compared to the control are denoted with *.