Figure 4. Correction of APC-induced bleeding by superFVa in the murine tail clip model.

Wild-type BalbC mice were injected intravenously with increasing doses of rhAPC or with saline. ^SuperFVa was injected intravenously 2 minutes prior to APC. Bleeding after tail clip is expressed as blood loss in µl blood per gram mouse. A) Blood loss during 20 minutes, and divided into B) first 10 minutes and C) second 10 minutes after tail clip. Error bars represent SEM.