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. 2014 Aug 15;9(8):e104741. doi: 10.1371/journal.pone.0104741

Figure 1. Role of Mincle in cell death induced inflammatory responses.

Figure 1

(A, B, C, D) The total neutrophil (A, C) and monocyte (B, D) numbers in the peritoneal cavity of WT C57BL/6 mice and Mincle-deficient mice 4 hours (A, B) or 16 hours (C, D) after i.p. injection of heat-shocked necrotic EL4 cells. (E, F) Myeloperoxidase activity in the liver (E) and serum levels of ALT (F) of mice challenged with i.p. injection of 300 mg/kg of Acetaminophen in C57BL/6 or Mincle- deficient mice. The data are combined results of 3 experiments and represented as means ±SEM (n =  total number of mice from the multiple experiments for each group). NS, not significant versus WT groups. PBS, WT mice injected with PBS.