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. 2014 Aug 15;9(8):e104952. doi: 10.1371/journal.pone.0104952

Table 3. Maximum percentage of inhibition of J. gossypiifolia against local effects produced by B. jararaca.

Activity Dose, route Inhibition (%)
Hemorrhagic 100 mg/kg, p.o. 56.1
Edematogenic* 200 mg/kg, i.p. 99.9
Myotoxic 50 mg/kg, i.p. 96.5

Percentage of inhibition was calculated as: [1 – (%activity of test mean –%activity of PBS control mean) ÷ (%activity of Bja control mean –%activity of PBS control mean)] ×100. *In the case of edematogenic activity, the last time point (120 min) of the paw thickness was considered.