Table 3. Maximum percentage of inhibition of J. gossypiifolia against local effects produced by B. jararaca.
Activity | Dose, route | Inhibition (%) |
Hemorrhagic | 100 mg/kg, p.o. | 56.1 |
Edematogenic* | 200 mg/kg, i.p. | 99.9 |
Myotoxic | 50 mg/kg, i.p. | 96.5 |
Percentage of inhibition was calculated as: [1 – (%activity of test mean –%activity of PBS control mean) ÷ (%activity of Bja control mean –%activity of PBS control mean)] ×100. *In the case of edematogenic activity, the last time point (120 min) of the paw thickness was considered.