Table 2. Extracted 7 SNPs with q<1 for the second dataset.
RS number | Allele | MAF | SNP function | Chr | Positiona | Associated gene symbol | For second dataset | Two stages of screening | |||
Type | Location | p F | q BH | p per | |||||||
rs9351963 | A/C | 0.328 | cSNP | intron | 6 | 73749861 | KCNQ5 | 3.31E–05 | 0.173 | * | 0.0289 |
rs11022922 | C/T | 0.376 | cSNP | intron | 14 | 63472498 | KCNH5 | 3.21E–04 | 0.802 | 1.0000 | |
rs3918305 | A/G | 0.402 | cSNP | intron | 12 | 109331162 | SVOP | 6.21E–04 | 0.802 | 1.0000 | |
rs3813627 | G/T | 0.435 | cSNP | NearGene–5 | 1 | 161195148 | TOMM40L | 7.62E–04 | 0.802 | 1.0000 | |
rs768172 | A/T | 0.441 | cSNP | intron | 7 | 95805703 | SLC25A13 | 7.87E–04 | 0.802 | 1.0000 | |
rs3813628 | A/C | 0.436 | cSNP | 5′UTR | 1 | 161196166 | TOMM40L | 1.02E–03 | 0.802 | 1.0000 | |
rs10815019 | A/G | 0.222 | cSNP | intron | 9 | 4547288 | SLC1A1 | 1.20E–03 | 0.802 | 1.0000 |
RS number: reference SNP identification number in dbSNP, MAF: minor allele frequency, Chr: chromosome number, i.e., a position in human genome GRCh37.p10 build 104, p F indicates a p value calculated using Fisher's exact test, q BH indicates adjusted p F value by the Benjamini-Hochberg method, p per indicates p values adjusted using a permutation test for multiple testing problems, * indicates p per<0.05. NearGene-5 indicates that the SNP is within 2 kb upstream of a gene.