Figure 1. Study of apoptosis-like features in platelets following aspirin treatment.

Mitochondrial transmembrane potential (red/green ratio) (A), PS exposure (PE-annexin V binding) (B) and ROS generation (C) were studied in control platelets, as well as in cells pre-treated with aspirin as indicated. In (A), CCCP (mitochondrial protonophore) has been employed as the positive control. Data are representative of five different experiments and expressed as mean±SD. (*p<0.05 as compared to ethanol-pretreated resting platelets).