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. 2014 Aug 15;9(8):e103813. doi: 10.1371/journal.pone.0103813

Table 3. Selection signatures in ancestral populations.

Estimated ancestral allele frequencies
OAR position AFR ASI SWA NEU CEU ITA SWE P-value Q-value Cand. gene Nr. genes Rank
1 7192190 0.15 0.08 0.16 0.55 0.69 0.04 0.38 1.7e-06 5.3e-03 TRPM8 19 8
1 237070498 0.87 0.95 0.91 0.48 0.24 0.77 0.35 1.4e-05 2.5e-02 GYG1 16 5
1 239424807 0.46 0.68 0.06 0.21 0.15 0.11 0.17 3.4e-05 4.8e-02 9
1 239491620 0.53 0.41 0.94 0.86 0.93 0.93 0.88 4.3e-05 5.6e-02 9
2 45500785 0.43 0.91 0.23 0.76 0.87 0.87 0.93 2.2e-06 6.4e-03 LPL 6 3
2 182607165 0.99 0.97 0.18 0.64 0.73 0.83 0.64 3.4e-08 1.8e-04 INSIG2 10 3
2 182672296 0.99 0.94 0.32 0.90 0.86 0.89 0.81 7.7e-07 2.8e-03 10
2 192231314 0.59 0.93 0.36 0.96 0.89 0.81 0.95 1.6e-05 2.8e-02 8
3 132478420 0.24 0.89 0.18 0.93 0.81 0.84 0.82 1.2e-06 3.9e-03 HOXC Inline graphic 54 1Inline graphic9
3 180860403 0.71 0.53 0.28 0.82 0.31 0.12 0.13 1.7e-05 2.8e-02 22
5 15522700 0.68 0.63 0.92 0.27 0.76 0.99 0.78 9.8e-06 2.0e-02 51
7 89519883 0.63 0.61 0.19 0.89 0.18 0.60 0.95 6.1e-10 5.2e-06 TSHR Inline graphic 6 3
8 31748642 0.84 0.93 0.94 0.16 0.63 0.47 0.19 2.8e-05 4.1e-02 PREP Inline graphic 6 1
11 18248852 0.35 0.32 0.82 0.64 0.94 0.96 0.92 1.3e-05 2.5e-02 NF1 Inline graphic 23 1
11 18325488 0.87 0.93 0.00 0.35 0.04 0.03 0.04 3.3e-16 7.2e-12 24 4
11 18335747 0.87 0.93 0.00 0.35 0.04 0.03 0.04 3.3e-16 7.2e-12 22 4
11 18433474 0.87 0.93 0.02 0.35 0.07 0.02 0.05 3.8e-15 5.4e-11 22 1
11 18440783 0.78 0.93 0.02 0.34 0.07 0.02 0.05 2.0e-14 2.2e-10 22 1
11 25704651 0.97 0.96 0.97 0.42 0.94 0.94 0.96 8.5e-06 1.9e-02 73
11 26284826 0.99 0.97 0.94 0.38 0.93 0.95 0.79 3.2e-05 4.6e-02 100
11 26571629 0.92 0.94 0.98 0.29 0.89 0.88 0.86 1.8e-05 2.8e-02 115
11 26872280 0.78 0.71 0.93 0.15 0.89 0.90 0.90 2.2e-07 9.5e-04 111
13 12120674 0.29 0.84 0.97 0.91 0.97 0.92 0.84 7.7e-06 1.8e-02 GATA3 6 1
13 62857560 0.52 0.62 0.65 0.98 0.67 0.92 0.36 3.6e-06 9.7e-03 ASIP Inline graphic 32 12
15 3706790 0.71 0.22 0.96 0.28 0.27 0.34 0.21 6.8e-06 1.7e-02 4
15 29856310 0.98 0.99 0.99 0.47 0.92 0.95 0.96 9.8e-06 2.0e-02 35
16 38696505 0.95 0.98 0.95 0.99 0.68 0.31 0.30 6.8e-07 2.7e-03 PRLR Inline graphic 18 2
17 4867509 0.91 0.95 0.85 0.54 0.18 0.58 0.17 1.8e-05 2.8e-02 TMEM154 9 1
18 19342316 0.90 0.79 0.67 0.35 0.75 0.10 0.09 1.9e-07 9.3e-04 ACAN Inline graphic 31 4
18 66470371 0.99 0.97 0.90 0.90 0.18 0.04 0.08 1.9e-09 1.3e-05 TRAF3 28 5
20 17381047 0.24 0.61 0.97 0.98 0.93 0.99 0.91 3.1e-08 1.8e-04 VEGFA Inline graphic 48 1
25 7517270 0.95 0.94 0.93 0.14 0.27 0.57 0.19 1.8e-05 2.8e-02 wool QTL Inline graphic 13

SNP with significant FLK value at the 5% FDR level, with estimated allele frequencies in all ancestral groups. The number of genes included in each region (1Mb up-or-downstream the position) and the rank of candidate genes within the region is also provided. Inline graphic: signatures of selection previously identified [4].