Table 3. Selection signatures in ancestral populations.
Estimated ancestral allele frequencies | |||||||||||||
OAR | position | AFR | ASI | SWA | NEU | CEU | ITA | SWE | P-value | Q-value | Cand. gene | Nr. genes | Rank |
1 | 7192190 | 0.15 | 0.08 | 0.16 | 0.55 | 0.69 | 0.04 | 0.38 | 1.7e-06 | 5.3e-03 | TRPM8 | 19 | 8 |
1 | 237070498 | 0.87 | 0.95 | 0.91 | 0.48 | 0.24 | 0.77 | 0.35 | 1.4e-05 | 2.5e-02 | GYG1 | 16 | 5 |
1 | 239424807 | 0.46 | 0.68 | 0.06 | 0.21 | 0.15 | 0.11 | 0.17 | 3.4e-05 | 4.8e-02 | 9 | ||
1 | 239491620 | 0.53 | 0.41 | 0.94 | 0.86 | 0.93 | 0.93 | 0.88 | 4.3e-05 | 5.6e-02 | 9 | ||
2 | 45500785 | 0.43 | 0.91 | 0.23 | 0.76 | 0.87 | 0.87 | 0.93 | 2.2e-06 | 6.4e-03 | LPL | 6 | 3 |
2 | 182607165 | 0.99 | 0.97 | 0.18 | 0.64 | 0.73 | 0.83 | 0.64 | 3.4e-08 | 1.8e-04 | INSIG2 | 10 | 3 |
2 | 182672296 | 0.99 | 0.94 | 0.32 | 0.90 | 0.86 | 0.89 | 0.81 | 7.7e-07 | 2.8e-03 | 10 | ||
2 | 192231314 | 0.59 | 0.93 | 0.36 | 0.96 | 0.89 | 0.81 | 0.95 | 1.6e-05 | 2.8e-02 | 8 | ||
3 | 132478420 | 0.24 | 0.89 | 0.18 | 0.93 | 0.81 | 0.84 | 0.82 | 1.2e-06 | 3.9e-03 | HOXC | 54 | 19 |
3 | 180860403 | 0.71 | 0.53 | 0.28 | 0.82 | 0.31 | 0.12 | 0.13 | 1.7e-05 | 2.8e-02 | 22 | ||
5 | 15522700 | 0.68 | 0.63 | 0.92 | 0.27 | 0.76 | 0.99 | 0.78 | 9.8e-06 | 2.0e-02 | 51 | ||
7 | 89519883 | 0.63 | 0.61 | 0.19 | 0.89 | 0.18 | 0.60 | 0.95 | 6.1e-10 | 5.2e-06 | TSHR | 6 | 3 |
8 | 31748642 | 0.84 | 0.93 | 0.94 | 0.16 | 0.63 | 0.47 | 0.19 | 2.8e-05 | 4.1e-02 | PREP | 6 | 1 |
11 | 18248852 | 0.35 | 0.32 | 0.82 | 0.64 | 0.94 | 0.96 | 0.92 | 1.3e-05 | 2.5e-02 | NF1 | 23 | 1 |
11 | 18325488 | 0.87 | 0.93 | 0.00 | 0.35 | 0.04 | 0.03 | 0.04 | 3.3e-16 | 7.2e-12 | 24 | 4 | |
11 | 18335747 | 0.87 | 0.93 | 0.00 | 0.35 | 0.04 | 0.03 | 0.04 | 3.3e-16 | 7.2e-12 | 22 | 4 | |
11 | 18433474 | 0.87 | 0.93 | 0.02 | 0.35 | 0.07 | 0.02 | 0.05 | 3.8e-15 | 5.4e-11 | 22 | 1 | |
11 | 18440783 | 0.78 | 0.93 | 0.02 | 0.34 | 0.07 | 0.02 | 0.05 | 2.0e-14 | 2.2e-10 | 22 | 1 | |
11 | 25704651 | 0.97 | 0.96 | 0.97 | 0.42 | 0.94 | 0.94 | 0.96 | 8.5e-06 | 1.9e-02 | 73 | ||
11 | 26284826 | 0.99 | 0.97 | 0.94 | 0.38 | 0.93 | 0.95 | 0.79 | 3.2e-05 | 4.6e-02 | 100 | ||
11 | 26571629 | 0.92 | 0.94 | 0.98 | 0.29 | 0.89 | 0.88 | 0.86 | 1.8e-05 | 2.8e-02 | 115 | ||
11 | 26872280 | 0.78 | 0.71 | 0.93 | 0.15 | 0.89 | 0.90 | 0.90 | 2.2e-07 | 9.5e-04 | 111 | ||
13 | 12120674 | 0.29 | 0.84 | 0.97 | 0.91 | 0.97 | 0.92 | 0.84 | 7.7e-06 | 1.8e-02 | GATA3 | 6 | 1 |
13 | 62857560 | 0.52 | 0.62 | 0.65 | 0.98 | 0.67 | 0.92 | 0.36 | 3.6e-06 | 9.7e-03 | ASIP | 32 | 12 |
15 | 3706790 | 0.71 | 0.22 | 0.96 | 0.28 | 0.27 | 0.34 | 0.21 | 6.8e-06 | 1.7e-02 | 4 | ||
15 | 29856310 | 0.98 | 0.99 | 0.99 | 0.47 | 0.92 | 0.95 | 0.96 | 9.8e-06 | 2.0e-02 | 35 | ||
16 | 38696505 | 0.95 | 0.98 | 0.95 | 0.99 | 0.68 | 0.31 | 0.30 | 6.8e-07 | 2.7e-03 | PRLR | 18 | 2 |
17 | 4867509 | 0.91 | 0.95 | 0.85 | 0.54 | 0.18 | 0.58 | 0.17 | 1.8e-05 | 2.8e-02 | TMEM154 | 9 | 1 |
18 | 19342316 | 0.90 | 0.79 | 0.67 | 0.35 | 0.75 | 0.10 | 0.09 | 1.9e-07 | 9.3e-04 | ACAN | 31 | 4 |
18 | 66470371 | 0.99 | 0.97 | 0.90 | 0.90 | 0.18 | 0.04 | 0.08 | 1.9e-09 | 1.3e-05 | TRAF3 | 28 | 5 |
20 | 17381047 | 0.24 | 0.61 | 0.97 | 0.98 | 0.93 | 0.99 | 0.91 | 3.1e-08 | 1.8e-04 | VEGFA | 48 | 1 |
25 | 7517270 | 0.95 | 0.94 | 0.93 | 0.14 | 0.27 | 0.57 | 0.19 | 1.8e-05 | 2.8e-02 | wool QTL | 13 |
SNP with significant FLK value at the 5% FDR level, with estimated allele frequencies in all ancestral groups. The number of genes included in each region (1Mb up-or-downstream the position) and the rank of candidate genes within the region is also provided. : signatures of selection previously identified [4].