Figure 2. Survival curves of intra-peritoneally infected 263K male and female Syrian hamsters. ~40 d old male (n = 10) and female (n = 11) hamsters were intra-peritoneally infected with 263K prions as described in Materials and Methods. Animals were sacrificed at advanced stage of clinical disease. Numbers in parenthesis note average incubation periods ± standard error. Survival curves were significantly different (P value = 0.0007).