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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Exp Brain Res. 2014 Apr 26;232(9):2775–2784. doi: 10.1007/s00221-014-3958-1

Fig 3.

Fig 3

Impact of in vitro alcohol treatment on NSCs and progenitors derived from the adult SVZ. Alcohol can directly impact these cells, but only at high doses a. At high doses alcohol inhibits neurosphere formation in vitro when added at the start of passaging. Alcohol concentrations of 100 mM or 1 M reduced the formation of neurospheres (p < 0.05) b. The viability of cultures in serum-free growth media at 24h post-alcohol exposure. Only the supraphysiological 1 M alcohol dose negatively impacts viability (p < 0.05) c. Viability of cultures in media plus 1% fetal bovine serum at 24h post-alcohol exposure. Again, the only dose negatively impacting viability is 1 M (p < 0.05), suggesting that the effects of 100 mM alcohol are not due to the death of cells in the neuropshere. All data expressed as Mean ± S.E.M. * p < 0.05