Figure 1. Arterial Pressure and Heart Rate.
Measurement of systolic arterial pressure (SAP), mean arterial pressure (MAP), diastolic arterial pressure (DAP), heart rate (HR) and intrinsic heart rate (iHR) using radiotelemetry. A) Average 1-hour recording of SAP, MAP and DAP. B) Average HR over a 1-hour period calculated from the AP recordings and iHR calculated from the AP recordings after simultaneous blockage of sympathetic and vagal tone to the heart with propranolol and methyl-atropine, respectively. C) HR response to intraperitoneal injection of methyl-atropine (ATR) and propranolol (PROP). S-P467L (black) and non-transgenic (gray) mice. *, P<0.05 vs NT (n=8).