Skip to main content
. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Hypertension. 2014 Jun 16;64(3):619–625. doi: 10.1161/HYPERTENSIONAHA.114.03633

Table 1. Contractile responses to angiotensin II (Ang II) in uterine arteries from SD and TgA rats at early gestation.

Maximal response to Ang II (Ang IIMAX) is expressed as % KMAX and sensitivity as pD2. Results are shown for intact, denuded arteries and arteries pre-incubated with indomethacin (10-5 mol/L) or L-NAME (10-4 mol/L) as indicated.

Variables measured Intact Denuded
SD TgA SD TgA
Ang IIMAX, % KMAX 91±5 109±4* 150±17† 108±4*
pD2 8.60±0.08 8.86±0.08* 9.14±0.2† 8.87±0.13
+ Indomethacin + L-NAME
SD TgA SD TgA
Ang IIMAX, % KMAX 111±15 92±7† 128±8† 110±13
pD2 8.79±0.08† 8.54±0.03†* 9.28±0.17† 8.82±0.01
*

p<0.05 vs SD;

†

p<0.05 vs intact arteries.