Fig. 2.

Signal-to-noise ratio for biological markers of bone turnover measured at 3 months in the Fracture Prevention Trial of postmenopausal women with osteoporosis. Bone turnover markers other than PINP were measured in a subset of 171 women in the teriparatide 20 mcg/day group and 175 women in the placebo group. PINP was measured in a subset of 254 women in the teriparatide 20 mcg/day group and 260 women in the placebo group from samples that had been stored frozen for at least 4 years and had been previously thawed at least twice [17]. DPD urinary deoxypyridine corrected for creatinine, NTX-I urinary N-terminal cross-linking telopeptide of type I collagen corrected for creatinine, Bone ALP bone alkaline phosphatase, PICP procollagen type I C propeptide, PINP intact procollagen type I N propeptide. Adapted from Eastell and colleagues [17]