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. 2014 Jun 12;111(4):716–725. doi: 10.1038/bjc.2014.325

Figure 3.

Figure 3

NDD0005 and MI-63 sensitise high MDR-1-expressing p53 mutant and wt neuroblastoma cells to vincristine in a concentration-dependent manner. Sensitivity of SKNBe2C cells to treatment for 72 h with vincristine alone or in combination with 1, 2 or 5 μM (A) NDD0005, (B) MI-63 or (C) RG7388. Sensitivity of SHSY5Y cells to treatment for 72 h with vincristine alone or in combination with 0.25x, 0.5x and 1 × 72-h GI50 concentrations of (D) NDD0005, (E) MI-63 or (F) RG7388. Data are shown as the average of at least three independent experiments and error bars represent s.e.m.