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. 2014 Jun 17;111(4):696–707. doi: 10.1038/bjc.2014.326

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Copyright © 2014 Cancer Research UK

This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Therapeutic effects of docetaxel on MMTV-PyVmT mice with Abcc10^−/− and Abcc10^+/+ genotypes. (A) Comparison of growth rates of MMTV-PyVmT;Abcc10^−/− (red line; n=9) mammary tumours and MMTV-PyVmT;Abcc10^+/+ tumours treated with vehicle (blue line; n=8). (B) Comparison of growth rates of MMTV-PyVmT;Abcc10^−/− (red line; n=9) mammary tumours and MMTV-PyVmT;Abcc10^+/+ tumours treated with docetaxel (blue line; n=9). ^†Death. (C) Kaplan–Meier curve analysis indicated increased survival of docetaxel-treated MMTV-PyVmT;Abcc10^−/− mice compared with wild-type docetaxel-treated mice (P=0.0298). Error bars denote mean±s.e.m.